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  • AutorenbildJuergen Mairhofer

enGenes development and manufacturing support

enGenes Biotech offers development and manufacturing support services that are highly relevant to companies wishing to develop cost-effective manufacturing processes for recombinant proteins.

enGenes can assist clients to rapidly construct economic, scalable and efficient production processes based on its world-leading enGenes-eXpress technology for growth-decoupled protein production that provides powerful efficiency advantages for added value and commercial edge.

enGenes offers a modular system of customer services for gene expression and protein production in Escherichia coli .

Modular service platform

Its services are particularly useful for producing difficult-to-express proteins. The service platform is   modular, being divided into a series of discrete steps that can be performed individually or in combination to cover all specific demands along the line from gene to protein.

The range of service options cover:

  • Cloning / Vector optimization

  • Generation of expression strain / Host cell engineering

  • Feasibility studies for application of enGenes-eXpress technology

  • Techno-economic analysis (TEA) of the planned production process

  • Lab scale fermentations and bioprocess optimization

  • Establishing of purification protocol and final purification

  • Scale-up runs

enGenes project support plans also meet individual documentation requirements to facilitate easy tech transfer to the client’s own facilities and quality management system.

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