enGenes Biotech GmbH | Biotech company
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End-to-end microbial solutions

for the recombinant production of proteins, plasmid DNA, and bioconjugates.

Accelerating your innovations through
bioprocess development and custom manufacturing.

ENGINEERING BIOLOGY
FROM START TO FINISH

enGenes Biotech is a CRO/CDMO 

uniting microbial innovation with complete bioprocessing expertise.

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Services

Supporting biopharma and biotech from technical feasibility to commercial availability.

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Products

Reagents to reduce your biprocessing costs, including affinity ligands and endonuclease.

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Ready to get started?

From concept to commercial scale, discuss your challenge with our experts.

Your competitive advantage

Unlock cost-efficient, scalable manufacturing for your target molecules with our E. coli-based technology platform. Achieve soluble expression of hard-to-express proteins using a growth-decoupled system, lower production costs through extracellular or continuous manufacturing, and accelerate your time-to-market with faster development.

Our expertise becomes your competitive advantage.

Some highlights

25 g/L 
extracellular

Extracellular fed-batch process achieved record target protein titers of 25 g/L in under 3 months, starting from a mg/L intracellular process.

40 days
continuous

Fully continuous E. coli-based production of recombinant proteins and plasmid DNA, maintaining stable productivity for at least 40 days.

> 2 g/L
plasmid DNA

Tackled cost challenges in pDNA production by pushing yields over 2 g/L and reducing downstream unit operations while maintaining product quality.

Endonuclease
for scale

The price of our endonuclease eXrase enables DNA removal in industrial biotech fermentation processes, improving scalability, foam control, and downstream processing. 

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